Yes and no.
Yes you have to be aware that taking up a bus trip in rural places will expose you to >10 hrs of uneasy road and bus-mates smoking, chewing tobacco or getting travel sick. And that you will have no facilities for a decent toilet break, not unless you fancy sharing it with thousands of beetles and other bugs.
Yes you need to be prepared for jumping up and down on a rail tracks thy remember English invasion in XIX century.
Yes, you may consider a life threatening a trip on tip of a truck going though a hilly road that is actually not a road yet. It may become a road in the next 5 years or so. You need to trust the driver as going through these roads ever day with all that carriage of people and things has made them very skilled off road drivers. While in Western world men and women seek adrenaline through competing on inaccessible terrain in Burma every man and women who can drive must have those skills mattered in order to survive. There is no mercy on a convoy of various vehicles verbose must know the drill otherwise it will fail for each of them. So whether a motorbike, a four wheel drive or a truck driver all of them must be well accustomed and at ease with whatever road condition the day is going to bring.
